Monday, October 7, 2013

DMARDs-disease-modifying antirheumatic drugs (DMARDs)

DMARDs-disease-modifying antirheumatic drugs (DMARDs)


Rheumatoid arthritis (RA) is a chronic, systemic autoimmune inflammatory arthritis that clinically manifests as joint pain, stiffness, and swelling. If left untreated, persistent synovial inflammation can progress to cartilage and bone destruction and ultimately to major long-term disability and mortality.

 Synthetic disease-modifying antirheumatic drugs (DMARDs), such as 

  • methotrexate, 
  • leflunomide, 
  • sulfasalazine, 


have markedly improved clinical symptoms and slowed joint damage in RA patients.

Biological drug



A substance that is made from a living organism or its products.  Biological drugs are  used in the prevention, diagnosis, or treatment of cancer and other diseases. Biological drugs include 

  1. Antibodies, 
  2. Interleukins 
  3. Vaccines. 


Also called biologic agent and biological agent.

90Y-Ibritumomab tiuxetan
ADEPT
Aldesleukin
Alemtuzumab
Bevacizumab
Bortezomib
Cetuximab
Dasatinib
Erlotinib
Everolimus
Gefitinib
Gemtuzumab
Imatinib
Interferon alpha
Interleukin-2
Iodine-131 tositumomab
Ipilimumab
Lapatinib
Lenalidomide
Panitumumab
Rituximab
Sorafenib
Sunitinib
Thalidomide
Trastuzumab
Vemurafenib 
By brand name

Afinitor®
Avastin®
BEXXAR®
Erbitux®
Glivec®
Herceptin®
IntronA®
Iressa®
MabCampath®
Mabthera®
Mylotarg®
Nexavar®
Proleukin®
Revlimid®
Roferon-A®
Sprycel®
Sutent®
Tarceva®
Thalidomid®
Tyverb®
Vectibix®
Velcade®
YERVOY™
Zelboraf®

Zevalin®